Why the study?
Does rivaroxaban prevent recurrent skin necrosis in a pediatric patient with severe protein S deficiency and warfarin-induced skin necrosis?
Population
n=1, 6-year-old girl with severe protein S deficiency due to a homozygous mutation, history of purpura…
Comparison
Rivaroxaban vs Warfarin
Design
Case_report
Follow-up
1 year
Authors
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May support rivaroxaban alternative in warfarin-induced necrosis; leaves open confirmation in pediatric protein S deficiency.
Does rivaroxaban prevent recurrent skin necrosis in a pediatric patient with severe protein S deficiency and warfarin-induced skin necrosis?
Rivaroxaban may be a valid anticoagulant alternative to vitamin K antagonists in patients with severe inherited protein S deficiency who experience warfarin-induced skin necrosis.
Martinelli et al. (2013) studied this question.
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