February 22, 2011HypertensionOpen Access

Trajectories of Depressive Episodes and Hypertension Over 24 Years

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Why the study?

Does an increasing trajectory of depressive episodes increase the risk of developing hypertension over time in adults?

Structured PICO

Does an increasing trajectory of depressive episodes increase the risk of developing hypertension over time in adults?

Population

10,302 adults (6,889 men and 3,413 women), London-based civil servants aged 35 to 55 years at baseline.

Intervention

Increasing depression trajectory (depressive episode defined as scoring ≥4 on the General Health Questionnaire-Depression subscale or using prescribed antidepressant medication)

Comparator

Low/transient depression trajectory

Outcome

Probability of hypertension (systolic/diastolic blood pressure ≥140/90 mm Hg or use of antihypertensive medication) over timesurrogate

Repeated depressive episodes over time are associated with a faster age-related increase in the risk of developing hypertension, becoming evident in later adulthood.

Discussion

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Implication

May warrant closer BP monitoring in aging adults with rising depression; leaves open whether treatment alters hypertension trajectories.

Cite This Study

Nabi et al. (2011) studied this question.

synapsesocial.com/papers/6a76ec9a7ecc675f86ae1efd https://doi.org/10.1161/hypertensionaha.110.164061

Topics

Hypertension management

View Full Paper

Ask AI

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Trajectories of Depressive Episodes and Hypertension Over 24 Years

Structured PICO

Discussion

Implication

Cite This Study

Topics

Trajectories of Depressive Episodes and Hypertension Over 24 Years

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider