Why the study?
Is plasma cholesteryl ester transfer associated with carotid intima-media thickness in type 2 diabetic and nondiabetic subjects?
Population
169 subjects, comprising 87 male and female subjects with type 2 diabetes and 82 control subjects.
Design
Cross-sectional
Authors
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CET associated with IMT in diabetes after adjustment; hypothesis-generating for CETP inhibition, needs prospective confirmation before practice change.
Is plasma cholesteryl ester transfer associated with carotid intima-media thickness in type 2 diabetic and nondiabetic subjects?
Plasma cholesteryl ester transfer is a positive determinant of carotid intima-media thickness, suggesting a potential role for CETP inhibitors in reducing cardiovascular risk in diabetes-associated hypertriglyceridemia.
Vries et al. (2005) studied this question.
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