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April 1, 2019Comprehensive physiology

Estrogens modulate adipose mass and the differential deposition of white, beige, and brown adipose tissues through estrogen receptors.

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Why the study?

Adipose profiles are depot dependent and influenced by sex steroid status, but estrogen receptor expression profiles in beige and brown adipocytes remain less well established.

Design

Review

Key result

Estrogens modulate adipose mass and the differential deposition of white, beige, and brown adipose tissues through estrogen receptors.

Authors

GBGabriel B. BernasochiJBJames R. BellESEvan R. Simpson

Discussion

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Overview

Adipose endocrine profiles merit attention in obesity care; leaves open targeted interventions by depot and sex hormone status.

PICO

E
Exposure / Comparator
Estrogens

This review highlights the complex role of estrogens and their receptors in regulating the endocrine, metabolic, and inflammatory profiles of different adipose tissue depots.

Cite This Study

Bernasochi et al. (2019) reported a review. Estrogens was evaluated. Estrogens modulate adipose mass and the differential deposition of white, beige, and brown adipose tissues through estrogen receptors.

synapsesocial.com/papers/6a76fb026789de8d0af6eeb7https://doi.org/10.1002/j.2040-4603.2019.tb00071.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Estrogens in Adipose Tissue Physiology and Obesity-Related Dysfunction2023 · 174 citations
  2. 2The influence of sex steroids on adipose tissue growth and function2014 · 48 citations
  3. 3The evolutionary impact and influence of oestrogens on adipose tissue structure and function2023 · 14 citations
  4. 4Adipose Tissue Heterogeneity: Depot-Specific Location and Functional Specialization in Obesity-Related Disease2026
  5. 5New Insights on the Environment of Sex Steroids in Adipose Tissue of Postmenopausal Women at Hormone Therapy2024