Key result
In healthy middle-aged men, the increase in mean arterial pressure during the cold pressor test did not significantly correlate with carotid artery reactivity (r=0.209, P=0.197).
Why the study?
Carotid artery reactivity to sympathetic stimulation is a novel test of vascular health, but the relationship between the increase in blood pressure and carotid artery diameter response during the test is not understood.
Does the increase in blood pressure mediate carotid artery dilation in response to sympathetic stimulation in healthy, middle-aged men?
Cross-Sectional (n=40)
Does the increase in blood pressure mediate carotid artery dilation in response to sympathetic stimulation in healthy, middle-aged men?
Effect estimate: r = 0.209
p-value: p=0.197
The characteristic increase in mean arterial pressure during sympathetic stimulation does not appear to mediate carotid artery vasomotion in healthy middle-aged men.
No takes yet. Share an insight, caveat, or question.
BP changes do not mediate CAR in healthy men; leaves open its added prognostic value beyond traditional risk factors.
Peace et al. (2019) conducted a cross-sectional in Healthy (n=40). Increase in mean arterial pressure during cold pressor test was evaluated on Correlation between resting mean arterial pressure and carotid artery reactivity (CAR%) (r = 0.209, p=0.197). In healthy middle-aged men, the increase in mean arterial pressure during the cold pressor test did not significantly correlate with carotid artery reactivity (r=0.209, P=0.197).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: