August 1, 1998AJP Heart and Circulatory Physiology
Arterial response during cold pressor test in borderline hypertension
Why the study?
Does the cold pressor test alter pulse-pressure amplification and arterial distensibility in subjects with borderline hypertension compared to normotensive controls?
Population
20 subjects (10 with borderline hypertension and 10 age- and sex-matched normotensive controls)
Comparison
Cold pressor test (CPT) vs Normotensive controls and baseline measurements
Design
Case-control
Authors
Discussion
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Member takes
Implication
May indicate blunted vascular reactivity in borderline hypertension; leaves open mechanisms and clinical relevance pending prospective studies.
Structured PICO
Does the cold pressor test alter pulse-pressure amplification and arterial distensibility in subjects with borderline hypertension compared to normotensive controls?
P
Population
20 subjects (10 with borderline hypertension and 10 age- and sex-matched normotensive controls)
I
Intervention
Cold pressor test (CPT)
C
Comparator
Normotensive controls and baseline measurements (before CPT)
O
Outcome
Carotid-brachial pulse-pressure amplification and changes in brachial and carotid distensibilitysurrogate
The cold pressor test reduces pulse-pressure amplification and arterial distensibility, with a blunted response observed in borderline hypertensive subjects compared to normotensive controls.
Cite This Study
Laflèche et al. (1998) studied this question.