Key result
Amiodarone therapy in adults with congenital heart disease caused significant adverse effects in 56% of patients, most commonly thyroid dysfunction, leading to drug discontinuation in 42%.
Why the study?
What is the incidence of adverse effects of amiodarone therapy in adults with congenital heart disease?
Observational (n=57)
No
What is the incidence of adverse effects of amiodarone therapy in adults with congenital heart disease?
Amiodarone therapy is highly effective for arrhythmias in adults with congenital heart disease but is frequently limited by a high rate of adverse effects (56%), particularly thyroid dysfunction.
Authors
No takes yet. Share an insight, caveat, or question.
Amiodarone adverse effects in ACHD warrant vigilant monitoring; hypothesis-generating and should not yet change practice.
Moore et al. (2018) conducted an observational in Adult congenital heart disease (ACHD) (n=57). Amiodarone was evaluated on Significant adverse effects. Amiodarone therapy in adults with congenital heart disease caused significant adverse effects in 56% of patients, most commonly thyroid dysfunction, leading to drug discontinuation in 42%.
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