Why the study?
Does enalapril maleate alter plasma levels of active and inactive renin in patients with renovascular hypertension?
Population
5 patients with renovascular hypertension (RVH) due to unilateral renal artery stenosis
Design
Case_series
Follow-up
chronic treatment (multiple days)
Authors
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Enalapril may acutely convert inactive to active renin in renovascular hypertension; leaves open confirmation of chronic dynamics in larger studies.
Does enalapril maleate alter plasma levels of active and inactive renin in patients with renovascular hypertension?
Enalapril treatment in renovascular hypertension suggests a conversion from inactive to active renin acutely, with both increasing chronically upon blood pressure normalization.
Ogawa et al. (1985) studied this question.
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