Why the study?
Does enalapril reduce blood pressure and improve hemodynamics in hypertensive patients?
Population
10 hypertensive patients
Comparison
Enalapril 20 mg orally twice daily for 3 months vs Pretreatment baseline (sequential study)
Design
Cohort
Follow-up
3 months
Authors
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Enalapril may improve hemodynamics in hypertension without tachycardia; leaves open confirmation in randomized trials before practice change.
Does enalapril reduce blood pressure and improve hemodynamics in hypertensive patients?
Enalapril effectively lowers blood pressure in hypertensive patients by reducing total peripheral resistance without causing reflex tachycardia or changing cardiac output.
Fouad et al. (1984) studied this question.
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