Key result
High mean platelet volume (high tertile) was associated with significantly increased odds of ischaemic ECG changes compared to lower values (OR 4.2; 95% CI 2.5-7.1; p=0.006).
Population
366 non-selected elderly subjects (both sexes, mean age 72.9 +/- 5.5 years)
Design
Cross-sectional
Authors
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May warrant caution interpreting MPV in elderly ECG assessment; hypothesis-generating and requires prospective validation before practice change.
Cross-Sectional (n=366)
Odds Ratio: 4.2 (95% CI 2.5–7.1)
p-value: p=0.006
Blood glucose, percent body fat, and ischaemic ECG changes are independent determinants of higher mean platelet volume in an elderly population.
Muscari et al. (2008) conducted a cross-sectional in Elderly population (n=366). High mean platelet volume (high tertile) vs. Lower mean platelet volume was evaluated on Ischaemic ECG changes (OR 4.2, 95% CI 2.5-7.1, p=0.006). High mean platelet volume (high tertile) was associated with significantly increased odds of ischaemic ECG changes compared to lower values (OR 4.2; 95% CI 2.5-7.1; p=0.006).
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