May 5, 2008Journal of Hypertension
Very low frequency blood pressure fluctuations: not only myogenic responsiveness
Key result
This editorial argues that very low frequency blood pressure fluctuations are driven by a complex interplay of myogenic responsiveness and sympathetic baroreflex mechanisms, rather than myogenic tone alone.
Design
Editorial
Authors
Discussion
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Implication
This editorial highlights the complex interplay between myogenic responsiveness and sympathetic baroreflex mechanisms in modulating very low frequency blood pressure variability.
PICO
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Population
Blood pressure variability
This editorial highlights the complex interplay between myogenic responsiveness and sympathetic baroreflex mechanisms in modulating very low frequency blood pressure variability.
Limitations
- Dihydropyridine L-type calcium channel blockers interfere with endogenous vasoconstrictors, attenuating neurohumoral contributions to BPV.
- Use of cross-spectral transfer function between MAP and TPR in a closed loop condition is invalid for demonstrating causality.
- Cross-spectral transfer function is invalid in closed-loop conditions to demonstrate MAP affecting TPR
- Nifedipine blocks both myogenic response and endogenous vasoconstrictors
Cite This Study
Julien et al. (2008) conducted an editorial in Blood pressure variability. This editorial argues that very low frequency blood pressure fluctuations are driven by a complex interplay of myogenic responsiveness and sympathetic baroreflex mechanisms, rather than myogenic tone alone.