Why the study?
Does 5-isosorbide mononitrate 60 mg once daily improve compliance and reduce angina attacks compared to 20 mg twice daily in patients with stable angina pectoris?
Does 5-isosorbide mononitrate 60 mg once daily improve compliance and reduce angina attacks compared to 20 mg twice daily in patients with stable angina pectoris?
A once-daily controlled-release formulation of 5-isosorbide mononitrate improves medication compliance and reduces angina frequency compared to a twice-daily regimen.
No takes yet. Share an insight, caveat, or question.
Supports once-daily 5-isosorbide mononitrate for stable angina to boost compliance and cut attacks; confirms RCT superiority over twice-daily dosing.
J.P. Brun (1994) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: