Key result
In patients undergoing chronic haemodialysis, a prolonged QTc interval was independently associated with increased total mortality (HR 2.16; 95% CI 1.20-3.91; P=0.011) and sudden cardiac death.
Why the study?
Does a prolonged QTc interval predict total mortality and sudden cardiac death in chronic haemodialysis patients?
Population
122 patients undergoing chronic haemodialysis, median age 71.3 years, 64.8% male, with high prevalence of…
Comparison
Prolonged QTc interval measured by… vs Normal QTc interval
Design
Case_series
Follow-up
median 3.9 years
Authors
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May support QTc monitoring for risk stratification in haemodialysis; hypothesis-generating and requires prospective validation.
Observational (n=122)
Does a prolonged QTc interval predict total mortality and sudden cardiac death in chronic haemodialysis patients?
Hazard Ratio: 2.16 (95% CI 1.2–3.91)
p-value: p=0.011
In chronic haemodialysis patients, a prolonged QTc interval is a strong independent predictor of both total mortality and sudden cardiac death.
Genovesi et al. (2013) conducted an observational in Chronic haemodialysis (n=122). Prolonged QTc interval vs. Normal QTc interval was evaluated on Total mortality (HR 2.16, 95% CI 1.20-3.91, p=0.011). In patients undergoing chronic haemodialysis, a prolonged QTc interval was independently associated with increased total mortality (HR 2.16; 95% CI 1.20-3.91; P=0.011) and sudden cardiac death.
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