Key result
A review of the literature highlights the importance of treating soft tissue sarcomas of the limbs with wide radical resections to obtain negative pathological margins and minimize local recurrence.
This literature review highlights the importance of wide radical resections with negative pathological margins to balance tumor excision and limb function preservation in soft tissue sarcomas.
Supports negative-margin resection in limb sarcomas; leaves open prospective trials on recurrence-function balance.
Soft tissue sarcomas (STS) are rare neoplasms (1% of all cancers in US with a prevalence of 10520 new cases/year) although there are more than 50 different histological type.The current management of STS is addressed to excision of the tumor and to preserve limb function as better as possible; respectingthis balance has been always a challenge for the orthopedic oncology and the importance of treating patients with such sarcomas with wideradical resections obtaining negative pathological margins has beenunderlined in many studies.
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Giuseppe Caff (2014) conducted a review in Soft tissue sarcomas of the limbs. Wide radical resections was evaluated on Local recurrence. A review of the literature highlights the importance of treating soft tissue sarcomas of the limbs with wide radical resections to obtain negative pathological margins and minimize local recurrence.
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