Key result
Direct oral anticoagulants and warfarin shared similar disease and outcome characteristics in patients with stroke or TIA, though one-third of sub-therapeutic warfarin patients received thrombolytics.
Why the study?
Clinical and imaging characteristics of patients receiving direct oral anticoagulants who present with transient ischaemic attack or stroke are lacking.
Do clinical, radiological characteristics, and functional outcomes differ between patients on direct oral anticoagulants versus warfarin presenting with acute stroke symptoms?
Observational
No
Do clinical, radiological characteristics, and functional outcomes differ between patients on direct oral anticoagulants versus warfarin presenting with acute stroke symptoms?
Patients on direct oral anticoagulants presenting with acute stroke or TIA have similar outcomes to those on warfarin, but are less likely to receive thrombolytic therapy due to a lack of DOAC level testing.
No takes yet. Share an insight, caveat, or question.
Descriptive characteristics of anticoagulated TIA/stroke patients are hypothesis-generating; leaves open whether findings alter DOAC management or trial design.
Valente et al. (2020) conducted an observational in Transient ischaemic attack or stroke. Direct oral anticoagulants vs. Warfarin was evaluated on Clinical, radiological characteristics and functional outcomes. Direct oral anticoagulants and warfarin shared similar disease and outcome characteristics in patients with stroke or TIA, though one-third of sub-therapeutic warfarin patients received thrombolytics.
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