Key result
Obesity unequally perturbs the endothelial glycocalyx in visceral versus subcutaneous adipose arteries, leading to a loss of Kir shear sensitivity and endothelial dysfunction in visceral arteries.
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Does not support Kir2.1-targeted interventions yet; leaves open its role in regional endothelial protection in obesity.
Ahn et al. (2021) studied Obesity. Obesity was evaluated on Endothelial function and Kir shear sensitivity in visceral versus subcutaneous adipose arteries. Obesity unequally perturbs the endothelial glycocalyx in visceral versus subcutaneous adipose arteries, leading to a loss of Kir shear sensitivity and endothelial dysfunction in visceral arteries.
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