Population
Neonatal rabbit heart (intact mammalian heart containing the full range of CK isoenzymes)
Design
Preclinical
Authors
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CK saturation during isovolumic work in neonatal rabbits; extends kinetic models but leaves open translation to humans.
The study demonstrates that creatine kinase kinetics in the intact neonatal rabbit heart differ between arrested and working states, operating under saturating conditions during isovolumic work.
McAuliffe et al. (1991) studied this question.
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