September 1, 1988AJP Heart and Circulatory Physiology

Interrelation between end-systolic pressure-volume and pressure-wall thickness relations

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Population

7 isolated blood-perfused canine hearts

Design

Preclinical

Authors

JSJochen D. SchipkeDüsseldorf University Hospital JAJoe AlexanderNTT (Japan)YHYasuhiko HarasawaKyushu University

Discussion

Member takes

Implication

Animal data support linear ESPTR approximation for LV contractility assessment in physiological ranges; leaves open human validation.

Structured PICO

Population

7 isolated blood-perfused canine hearts

Intervention

Measurement of end-systolic pressure-thickness relationship (ESPTR) over wide volume ranges and assessment of contractility changes

Outcome

Shape of the end-systolic pressure-thickness relationship (ESPTR) and its response to changes in left ventricular contractile statesurrogate

The end-systolic pressure-thickness relationship can be used to assess left ventricular contractility in vivo within physiological pressure ranges, provided its curvilinear nature at lower pressures is accounted for.

Cite This Study

Schipke et al. (1988) studied this question.

synapsesocial.com/papers/6a77a4c14fe2e6ffd8ecd574 https://doi.org/10.1152/ajpheart.1988.255.3.h679

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Interrelation between end-systolic pressure-volume and pressure-wall thickness relations

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Interrelation between end-systolic pressure-volume and pressure-wall thickness relations

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider