Why the study?
The clinical value of α-HBDH, cTnI, and BNP in the perioperative diagnosis of heart failure in children with congenital heart disease required evaluation.
Does the measurement of α-HBDH, cTnI, and BNP improve the perioperative diagnosis of heart failure in children with congenital heart disease?
Does the measurement of α-HBDH, cTnI, and BNP improve the perioperative diagnosis of heart failure in children with congenital heart disease?
The combined preoperative measurement of cTnI and BNP provides high diagnostic accuracy for identifying perioperative heart failure in children undergoing surgery for congenital heart disease.
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May aid perioperative HF risk stratification in pediatric CHD; leaves open need for prospective validation before practice change.
Yin et al. (2025) studied this question.
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