Human cardiac troponin-C is a highly conserved protein consisting of 161 amino acids, identical to ox heart troponin-C.
Answers are grounded in this paper and cite their sources.
High conservation of cardiac troponin-C supports cross-species animal models; leaves open functional validation in human disease.
The amino acid sequence of human cardiac troponin-C (TN-C) has been rabbit cardiac TN-C. These results show that troponin-C is one of the Edman degradation. The sequence, which consists of 161 amino acid residues, is identical to that of the ox heart and as such is capable of binding three calcium ions. It differs at only one position from that of rabbit cardiac TN-C. These results show that troponin C is one of the most highly conserved proteins known.
No takes yet. Share an insight, caveat, or question.
Roher et al. (1986) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: