Why the study?
Does ACE gene polymorphism correlate with carotid intima-media thickness or left ventricular mass index in adolescents with hypertension?
Population
178 adolescents, comprising 120 with hypertension and 58 normotensive controls
Comparison
Angiotensin-converting enzyme gene polymorphism vs Comparison between different ACE genotypes and…
Design
Cross-sectional
Authors
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ACE genotyping not warranted for target-organ assessment in hypertensive adolescents; leaves open other genetic contributions to early IMT and LVMI.
Does ACE gene polymorphism correlate with carotid intima-media thickness or left ventricular mass index in adolescents with hypertension?
ACE genotype polymorphism does not correlate with the severity of target-organ damage (IMT and LVMI) in adolescents with hypertension.
Páll et al. (2004) studied this question.
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