Key result
Increased daytime systolic blood pressure variability was associated with significantly greater progression of carotid intima-media thickness (0.11 vs 0.05 mm/y; P<0.005).
Why the study?
Does increased daytime systolic blood pressure variability predict the progression of early carotid atherosclerosis in patients aged >55 years?
Population
286 patients aged >55 years
Comparison
Increased daytime systolic blood pressure… vs Lower daytime systolic blood pressure variability
Design
Cohort
Follow-up
3.3 years
Authors
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May aid risk stratification in patients >55 years; hypothesis-generating and should not yet change practice.
Cohort (n=286)
Does increased daytime systolic blood pressure variability predict the progression of early carotid atherosclerosis in patients aged >55 years?
Absolute Event Rate: 0.11% vs 0.05%
p-value: p=<0.005
Increased daytime systolic blood pressure variability is a strong predictor of early carotid atherosclerosis progression and cardiovascular events.
Sander et al. (2000) conducted a cohort in Early carotid atherosclerosis (n=286). Increased systolic blood pressure variability vs. Lower systolic blood pressure variability was evaluated on Progression of intima-media wall thickness (IMT) (p=<0.005). Increased daytime systolic blood pressure variability was associated with significantly greater progression of carotid intima-media thickness (0.11 vs 0.05 mm/y; P<0.005).
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