January 1, 1991European Respiratory JournalOpen Access

Effects of sodium-nitroprusside and urapidil on gas exchange and ventilation-perfusion relationships in patients with congestive heart failure

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Why the study?

Does urapidil alter gas exchange and ventilation-perfusion relationships less than sodium nitroprusside in patients with congestive heart failure?

Population

7 patients with congestive heart failure (CHF)

Comparison

Urapidil vs Sodium nitroprusside (SNP)

Authors

SAS Adnot PRP Radermacher PAP Andrivet

Discussion

Member takes

Implication

May favor urapidil over SNP to limit hypoxemia in CHF; hypothesis-generating and should not yet change practice.

Structured PICO

Does urapidil alter gas exchange and ventilation-perfusion relationships less than sodium nitroprusside in patients with congestive heart failure?

Population

7 patients with congestive heart failure (CHF)

Intervention

Urapidil

Comparator

Sodium nitroprusside (SNP)

Outcome

Gas exchange and ventilation-perfusion (Va/Q) relationships (including arterial PO2 and fractional perfusion to low Va/Q ratios)surrogate

Urapidil alters gas exchange and ventilation-perfusion relationships less than sodium nitroprusside in patients with congestive heart failure, avoiding the decrease in arterial PO2 seen with SNP.

Cite This Study

Adnot et al. (1991) studied this question.

synapsesocial.com/papers/6a77cf9c137c7dcc81be1602 https://doi.org/10.1183/09031936.93.04010069

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Effects of sodium-nitroprusside and urapidil on gas exchange and ventilation-perfusion relationships in patients with congestive heart failure

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effects of sodium-nitroprusside and urapidil on gas exchange and ventilation-perfusion relationships in patients with congestive heart failure

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider