Why the study?
Does oral prazosin provide similar cardiocirculatory improvements compared to nitroprusside in patients with chronic refractory congestive heart failure?
Population
n=11 chronic coronary patients with refractory congestive heart failure.
Comparison
Prazosin (oral) vs Nitroprusside
Design
Other
Follow-up
6 hours
Authors
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May support oral prazosin for ambulatory refractory HF; leaves open randomized confirmation of long-term outcomes.
Does oral prazosin provide similar cardiocirculatory improvements compared to nitroprusside in patients with chronic refractory congestive heart failure?
Oral prazosin produces similar favorable hemodynamic effects to nitroprusside in refractory heart failure, suggesting it is an effective vasodilator for long-term ambulatory therapy.
Awan et al. (1978) studied this question.
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