Why the study?
It was sought to determine whether patients from a family physician's practice have an association between 25(OH)D levels and primary arterial hypertension.
Do higher 25(OH)D levels prevent primary arterial hypertension in primary care patients?
Do higher 25(OH)D levels prevent primary arterial hypertension in primary care patients?
This study found no significant association between vitamin D levels and the presence of primary arterial hypertension in a primary care population.
No association found; leaves open any causal link between vitamin D and hypertension pending prospective trials.
This study seeks to determine whether patients from a family physician’s practice have an association between 25(OH)D levels and primary arterial hypertension (AH). The study included a total of 1068 patients who were tested for vitamin D status. Data from their outpatient medical records were analysed: sex, age, body mass index, glomerular filtration rate, and the history of AH. Primary arterial hypertension was diagnosed in 63% of the patients. The mean vitamin D level in the study population was 25 ng/ml, and the largest group, or 36%, was found to have vitamin D deficiency (20–29 ng/ml). Odds ratio (OR) for hypertension was not inversely correlated with higher vitamin D levels. No statistically significant increase was observed in OR in a multi-factor analysis. The relevant hypertension ORs were 1.8 (0.4–7.5), 1.1 (0.3–4.5), 1.7 (0.4–7.2) and 0.7 (0.1–4.8) 30 ng/ml to 45 ng/ml, 20 to 29 ng/ml, 10 to 19 ng/ml, and < 10 ng/ml compared to the group of ³ 45 ng/ml. No association was found between 25(OH)D levels and the primary arterial hypertension in study participants.
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Požarskis et al. (2023) studied this question.
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