Why the study?
Does flow cytometry correlate with turbidometric platelet aggregation in assessing platelet reactivity in patients with atherosclerotic vascular disease?
Population
20 adult patients with atherosclerotic vascular disease
Comparison
Assessment of platelet activation by flow… vs Turbidometric platelet aggregation
Design
Cross-sectional
Authors
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Supports flow cytometry fibrinogen binding as a whole-blood platelet reactivity assay; leaves open outcome validation before clinical adoption in vascular disease.
Does flow cytometry correlate with turbidometric platelet aggregation in assessing platelet reactivity in patients with atherosclerotic vascular disease?
Flow cytometry assessment of fibrinogen binding to activated platelets correlates well with the slope of turbidometric aggregation, offering a method to assess platelet reactivity in minimally altered whole blood.
García et al. (2007) studied this question.
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