Why the study?
Does flow cytometry correlate with optical aggregometry in evaluating ADP-induced platelet activation in healthy donors and patients undergoing coronary stenting?
Population
12 healthy donors and 13 patients undergoing coronary stenting
Comparison
Flow cytometry measuring CD62P and PAC-1… vs Optical aggregometry
Design
Cross-sectional
Authors
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CD62P by flow cytometry may correlate with aggregometry for platelet assessment; leaves open its role in guiding antiplatelet therapy post-stenting.
Does flow cytometry correlate with optical aggregometry in evaluating ADP-induced platelet activation in healthy donors and patients undergoing coronary stenting?
Flow cytometry quantification of platelet markers, particularly CD62P, tightly correlates with optical aggregometry and can predict aggregation response to ADP in patients on antiplatelet therapy.
Sbrana et al. (2007) studied this question.
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