Why the study?
Does captopril plasma concentration correlate with its antihypertensive and biological effects in hypertensive patients?
Does captopril plasma concentration correlate with its antihypertensive and biological effects in hypertensive patients?
Free unchanged captopril plasma monitoring is not an adequate indicator of potential responsiveness to its blood pressure lowering effects due to a lack of correlation between bioavailability and DBP reduction.
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Plasma captopril monitoring may not predict antihypertensive response; hypothesis-generating for prolonged effects beyond detectable levels.
Richer et al. (1984) studied this question.
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