Why the study?
Does terfenadine inhibit sodium current in canine atrial myocytes?
Population
Canine atrial myocytes
Design
Preclinical
Authors
Loading...
Hypothesis-generating for terfenadine cardiotoxicity; human studies needed before clinical relevance.
Does terfenadine inhibit sodium current in canine atrial myocytes?
Terfenadine acts as a potent sodium channel blocker in canine atrial myocytes, providing a potential mechanism for its known cardiac side effects.
Lu et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: