Why the study?
Dingji Fumai Decoction is widely used clinically for ventricular premature contraction, but a trial was needed to evaluate its safety and effectiveness.
Does Dingji Fumai Decoction combined with metoprolol improve symptoms and reduce VPC frequency in patients with ventricular premature contraction?
Population
144 patients with ventricular premature contraction
Comparison
DFD combined with metoprolol vs metoprolol combined with placebo
Design
Double-blinded randomized placebo-controlled trial
Follow-up
12 weeks
Authors
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Supports adding DFD to metoprolol for VPC symptom relief; extends RCT evidence for herbal adjuncts in arrhythmia.
Does Dingji Fumai Decoction combined with metoprolol improve symptoms and reduce VPC frequency in patients with ventricular premature contraction?
The addition of Dingji Fumai Decoction to metoprolol may improve symptoms and reduce the burden of ventricular premature contractions over 12 weeks.
Liang et al. (2020) studied this question.
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