Why the study?
Does intravenous capsaicin injection elicit the pulmonary chemoreflex or cardiovascular changes in conscious humans?
Population
3 normal subjects
Comparison
Central and peripheral intravenous injections of… vs Control solution
Design
Other
Follow-up
immediate (seconds)
Authors
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Intravenous capsaicin produces sensations without pulmonary chemoreflex or hemodynamic shifts in conscious humans; leaves open lung nociceptor contributions to sensation.
Does intravenous capsaicin injection elicit the pulmonary chemoreflex or cardiovascular changes in conscious humans?
Intravenous capsaicin in conscious humans produces dose-dependent sensations and coughing without evoking the pulmonary chemoreflex or cardiovascular changes, suggesting a nociceptive system in the lung parenchyma.
Winning et al. (1986) studied this question.
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