Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 9, 2026Signal Transduction and Targeted TherapyOpen Access

Post-translational modifications in metabolic reprogramming: implications for metabolic therapy and immunotherapy in cancer

View Full Paper
Ask AI
Bookmark
Share

Authors

SCSi-Jie ChenMerck & Co., Inc., Rahway, NJ, USA (United States)SYShi-Wei YueTongji HospitalYZYun-Pu ZhangTongji Hospital

Discussion

Loading...

Member takes

Overview

Review demonstrates how post-translational modifications govern metabolic reprogramming in cancer, suggesting new therapeutic strategies.

Key Points

  • This review aims to elucidate the role of post-translational modifications in cancer metabolism and their implications for therapy.
  • Review of literature on post-translational modifications and cancer metabolism
  • Analysis of the regulatory role of PTMs in metabolic pathways
  • Integration of recent advances in PTM networks and therapeutic strategies.
  • PTMs serve as master regulators of cancer metabolism and immune modulation.
  • Key metabolic pathways regulated by PTMs include glucose, lipid, and amino acid utilization.
  • Emerging therapies targeting PTMs show potential for enhancing treatment efficacy.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a782cfa2e1896536c83fbaahttps://doi.org/10.1038/s41392-026-02862-7
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Metabolic Fuel, Molecular Code: How Cancer Rewires Metabolite-Driven Post-Translational Modifications to Shape Tumor Fate2026
  2. 2Metabolism-driven posttranslational modifications and immune regulation: Emerging targets for immunotherapy.2025 · 20 citations
  3. 3Molecular Mediators of Metabolic Reprogramming in Cancer: Mechanisms, Regulatory Networks, and Therapeutic Strategies2025 · 29 citations
  4. 4Metabolism in Tumor: Mechanisms and Therapeutic Perspectives2026
  5. 5Rewiring tumor metabolism: heterogeneity, oncometabolites, and adaptive plasticity2026