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November 1, 2001Journal of Cardiovascular Pharmacology

Endothelial Function in Patients with Chronic Heart Failure

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Population

Patients with chronic heart failure

Design

Review

Authors

Uri ElkayamHeart Failure / Cardiomyopathy MPManish PrakashUniversity of Southern California SSShunmugaraja SubbiahUniversity of Southern California

Discussion

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Implication

Endothelial assessment may refine HF risk stratification; leaves open whether targeted vasoregulation improves perfusion in trials.

Structured PICO

P

Population

Patients with chronic heart failure

Highlights the role of the endothelium as a mediator of vasoregulation and tissue perfusion in chronic heart failure.

Cite This Study

Elkayam et al. (2001) studied this question.

synapsesocial.com/papers/6a782d944fe2e6ffd8ed4477 https://doi.org/10.1097/00005344-200111002-00012

Topics

Heart failure HFrEF treatment

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Mechanisms and implications of endothelial dysfunction in congestive heart failure1997 · 75 citations
2Endothelial Control of Arterial Distensibility Is Impaired in Chronic Heart Failure1995 · 281 citations
3Impaired acetylcholine-mediated vasodilation in patients with congestive heart failure. Role of endothelium-derived vasodilating and vasoconstricting factors.1993 · 225 citations
4Endothelium-dependent dilation of the coronary microvasculature is impaired in dilated cardiomyopathy.1990 · 445 citations
5What We Know and Don’t Know About l -Arginine and NO2000 · 83 citations