Why the study?
Are endothelium-dependent and endothelium-independent vasodilatory responses impaired in patients with chronic heart failure due to non-ischaemic heart disease compared to healthy volunteers?
Are endothelium-dependent and endothelium-independent vasodilatory responses impaired in patients with chronic heart failure due to non-ischaemic heart disease compared to healthy volunteers?
Both endothelium-dependent and endothelium-independent peripheral vasodilatory responses are significantly impaired in patients with symptomatic chronic heart failure due to non-ischaemic heart disease, and this impairment correlates with disease severity.
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Impaired vasodilatory responses associate with NYHA class in non-ischaemic HF; leaves open causal role and therapeutic implications.
Nakamura et al. (1996) studied this question.
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