Key result
The lowest quartile of forced vital capacity increased the risk of incident type 2 diabetes compared to the highest quartile in men (HR 1.6; 95% CI 1.3-2.0) and women (HR 1.7; 95% CI 1.3-2.1).
Why the study?
Does lower vital capacity predict incident type 2 diabetes in middle-aged adults without diabetes?
Population
11,479 middle-aged adults without diabetes at baseline from the Atherosclerosis Risk in Communities Study
Comparison
Lowest quartile of forced vital capacity vs Highest quartile of forced vital capacity
Design
Cohort
Follow-up
9 years
Authors
Loading...
Lower forced vital capacity was associated with incident diabetes; hypothesis-generating for lung function as a risk marker and requires prospective validation.
Cohort (n=11,479)
Yes
Does lower vital capacity predict incident type 2 diabetes in middle-aged adults without diabetes?
Effect estimate: HR 1.6 (men), HR 1.7 (women) (95% CI 1.3-2.0 (men), 1.3-2.1 (women))
Lower vital capacity is an independent predictor of incident type 2 diabetes in middle-aged adults, suggesting pulmonary factors may be related to insulin resistance risk.
Yeh et al. (2005) conducted a cohort in Risk of incident type 2 diabetes (n=11,479). Lowest quartile of forced vital capacity (% predicted) vs. Highest quartile of forced vital capacity (% predicted) was evaluated on Incident type 2 diabetes (HR 1.6 (men), HR 1.7 (women), 95% CI 1.3-2.0 (men), 1.3-2.1 (women)). The lowest quartile of forced vital capacity increased the risk of incident type 2 diabetes compared to the highest quartile in men (HR 1.6; 95% CI 1.3-2.0) and women (HR 1.7; 95% CI 1.3-2.1).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: