Population
Human peripheral blood mononuclear cells from 15 normal, healthy adult volunteers and cord blood lymphocytes…
Comparison
In vitro exposure to a panel of enteroviral… vs In vitro exposure to cardiovirus…
Design
Preclinical
Authors
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Adult CD4+ T-cell recognition of conserved enteroviral antigens may guide vaccine design; leaves open neonatal immunity implications pending in vivo studies.
This study demonstrates that human CD4+ T cells recognize a common enterovirus group antigen, regardless of specific neutralizing antibody titers.
Beck et al. (1990) studied this question.
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