Key result
Hypertrophic cardiomyopathy was associated with significantly abnormal atrioventricular junction motion, including a 16-fold higher VDS/MVED ratio at the lateral AVJ compared to healthy volunteers.
Why the study?
Does CMR-based atrioventricular junction motion analysis detect differences in mitral annular excursion and recoil between HCM patients and healthy volunteers?
Case-Control (n=38)
Yes
Does CMR-based atrioventricular junction motion analysis detect differences in mitral annular excursion and recoil between HCM patients and healthy volunteers?
Absolute Event Rate: 0.141% vs 0.009%
p-value: p=<0.001
CMR-based atrioventricular junction motion analysis is a practical method that can detect significant regional systolic and diastolic dysfunction in HCM patients despite preserved global ejection fraction.
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May aid detection of regional dysfunction in HCM despite preserved EF; leaves open its prognostic utility and clinical role.
Saba et al. (2014) conducted a case-control in Hypertrophic cardiomyopathy (n=38). Hypertrophic cardiomyopathy vs. Healthy volunteers was evaluated on VDS/MVED ratio at the lateral atrioventricular junction (p=<0.001). Hypertrophic cardiomyopathy was associated with significantly abnormal atrioventricular junction motion, including a 16-fold higher VDS/MVED ratio at the lateral AVJ compared to healthy volunteers.
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