Key result
Aging is associated with systemic and cardiac alterations in vascular tone, hemostasis, and vascular repair/angiogenesis, which may contribute to senescent cardiac pathology.
Population
United States population over the age of 65 with or at risk for ischemic cardiovascular disease
Design
Review
Authors
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Does not yet alter geriatric CVD management; leaves open whether vascular-targeted therapies can mitigate age-related cardiac senescence.
Understanding the biology of aging-associated vascular dysfunction is fundamental for the development of targeted therapeutics for cardiovascular disease in older individuals.
Weinsaft et al. (2001) conducted a review in Ischemic cardiovascular disease. Aging was evaluated. Aging is associated with systemic and cardiac alterations in vascular tone, hemostasis, and vascular repair/angiogenesis, which may contribute to senescent cardiac pathology.
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