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September 14, 2023Journal of Clinical MedicineOpen Access

Clinical Characteristics and Prognostic Impact of Short Physical Performance Battery in Hospitalized Patients with Acute Heart Failure—Results of the PROFUND-IC Registry

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Key result

An SPPB score > 5 in hospitalized acute heart failure patients was associated with a higher probability of survival at 1 year compared to an SPPB ≤ 5 (OR 6.01; 95% CI 1.90-18.30; P=0.007).

Why the study?

To evaluate the clinical characteristics of hospitalized patients with acute heart failure and determine their prognosis according to the Short Physical Performance Battery (SPPB) scale.

Does the Short Physical Performance Battery (SPPB) score predict mortality and readmission in hospitalized patients with acute heart failure?

Population

482 hospitalized patients with acute heart failure and NT-ProBNP > 300 pg in Spain

Comparison

SPPB score ≤ 5 vs SPPB score > 5

Design

Observational, prospective, multicenter cohort study

Follow-up

1 year

Authors

LLLidia López-GarcíaNLNoël Lorenzo-VillalbaJMJuan Igor Molina-Puente

Discussion

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Member takes

Overview

Characterizes multipathological acute HF inpatients; leaves open whether frailty-targeted strategies improve outcomes.

Study Design

Type

Cohort (n=482)

Multicenter

Yes

Structured PICO

Does the Short Physical Performance Battery (SPPB) score predict mortality and readmission in hospitalized patients with acute heart failure?

P
Population
482 patients admitted to internal medicine departments with acute heart failure and NT-ProBNP > 300 pg, followed for up to 1 year to assess mortality and readmission.
E
Exposure
Short Physical Performance Battery (SPPB) score ≤ 5 (indicating higher frailty)
C
Comparator
Short Physical Performance Battery (SPPB) score > 5 (indicating lower frailty)
O
Outcome
Overall mortality, HF mortality, and readmission at 30 days, 6 months, and 1 yearhard clinical

Main Result

Odds Ratio: 6.01 (95% CI 1.9–18.3)

p-value: p=0.007

The SPPB is a valid tool for identifying frailty and predicting 30-day, 6-month, and 1-year mortality in patients hospitalized with acute heart failure.

Cite This Study

López-García et al. (2023) conducted a cohort in Acute heart failure (n=482). Short Physical Performance Battery (SPPB) score > 5 vs. SPPB score ≤ 5 was evaluated on Survival at 1 year (OR 6.01, 95% CI 1.90-18.30, p=0.007). An SPPB score > 5 in hospitalized acute heart failure patients was associated with a higher probability of survival at 1 year compared to an SPPB ≤ 5 (OR 6.01; 95% CI 1.90-18.30; P=0.007).

synapsesocial.com/papers/6a789caca0847c3df1eceee9https://doi.org/10.3390/jcm12185974
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic significance of the short physical performance battery in patients with congestive heart failure: clinical and nutritional correlates2026
  2. 2Prognostic role of short physical performance battery in elderly hospitalized atrial fibrillation patients2025 · 3 citations
  3. 3Association Between the Short Physical Performance Battery and Hospitalization-Associated Disability in Older Patients With Heart Failure2026
  4. 4The short physical performance battery and incident heart failure among older women: the OPACH study2021 · 12 citations
  5. 5The benefit of the use of short physical performance battery test in elderly patients in cardiac rehabilitation2021 · 3 citations