Key result
18F-FDG PET/CT imaging demonstrated high diagnostic accuracy for early identification of confirmed CIED generator pocket infection requiring extraction (AUC 0.98, sensitivity 97%, specificity 98%).
Why the study?
Does 18F-FDG PET/CT imaging accurately diagnose early cardiac implantable electronic device generator pocket infection in patients with CIEDs?
Observational (n=86)
Does 18F-FDG PET/CT imaging accurately diagnose early cardiac implantable electronic device generator pocket infection in patients with CIEDs?
Effect estimate: AUC 0.98
p-value: p=<0.001
18F-FDG PET/CT provides high diagnostic accuracy for the early detection of CIED generator pocket infections, potentially guiding extraction decisions even when clinical signs are subtle.
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May aid early CIED pocket infection detection when signs are subtle; leaves open prospective validation before routine adoption.
Ahmed et al. (2015) conducted an observational in Suspected cardiac implantable electronic device (CIED) generator pocket infection (n=86). 18F-FDG PET/CT imaging vs. Patients without confirmed infection or controls was evaluated on Confirmed CIED generator pocket infection requiring extraction (AUC 0.98, p=<0.001). 18F-FDG PET/CT imaging demonstrated high diagnostic accuracy for early identification of confirmed CIED generator pocket infection requiring extraction (AUC 0.98, sensitivity 97%, specificity 98%).
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