Why the study?
Can a human cardiac troponin I immunoassay differentiate cardiac from skeletal muscle injury across various animal species?
Population
Cardiac and skeletal muscle tissues from various species (large mammals, small mammals, birds, and fish)
Design
Preclinical
Authors
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Human cTnI immunoassays may aid cardiac injury detection in mammalian models; leaves open cross-species utility in birds and fish.
Can a human cardiac troponin I immunoassay differentiate cardiac from skeletal muscle injury across various animal species?
A human cTnI immunoassay can effectively differentiate cardiac from skeletal muscle injury in mammals, but its utility decreases in birds and is unlikely to be useful in fish.
O’Brien et al. (1997) studied this question.
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