Key result
Various methods, including NO microsensors, electron spin resonance, and fluorescent probes, allow real-time measurement of vascular NO and ROS, though electrochemical sensors require calibration.
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Electrochemical NO sensors require calibration before clinical endothelial assessment; leaves open validation of microsensors for routine vascular research.
This review outlines the current methodologies and limitations for measuring NO and ROS in vascular tissues, emphasizing the potential of miniaturized electrochemical microsensors for real-time in situ evaluation of endothelial function.
Rodríguez‐Rodríguez et al. (2012) conducted a review in Endothelial dysfunction and cardiovascular disease. Measurement methods for vascular NO and ROS was evaluated. Various methods, including NO microsensors, electron spin resonance, and fluorescent probes, allow real-time measurement of vascular NO and ROS, though electrochemical sensors require calibration.
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