Key result
Early recurrence of atrial tachyarrhythmia within 3 months after surgical AF ablation strongly predicted late recurrence, with hazard ratios of 2.84, 16.70, and 119.75 for months 1, 2, and 3.
Why the study?
Little evidence exists regarding current guideline recommendations on the blanking period after surgical AF ablation.
Does early recurrence of atrial tachyarrhythmia predict late recurrence in patients undergoing surgical ablation for atrial fibrillation?
Cohort (n=259)
Does early recurrence of atrial tachyarrhythmia predict late recurrence in patients undergoing surgical ablation for atrial fibrillation?
Effect estimate: HR 2.84, 16.70, and 119.75
p-value: p=< .001
Early recurrence of atrial tachyarrhythmia within 3 months after surgical AF ablation strongly predicts late recurrence, suggesting the standard 3-month blanking period may need to be redefined.
ERAT after surgical AF ablation is hypothesis-generating; leaves open optimal blanking period definition pending prospective trials.
BACKGROUND: Atrial tachyarrhythmias (ATAs) are common within the 3-month blanking period after catheter ablation of atrial fibrillation (AF). However, little evidence is available regarding the current guidelines on the blanking period after surgical AF ablation. We investigate the incidence and significance of early recurrence of atrial tachyarrhythmia (ERAT) and evaluate the optimal blanking period after surgical AF ablation. METHODS: Data from 259 patients who underwent surgical AF ablation from 2009 to 2016 were collected. ERAT was defined as documented ATA episodes lasting for 30 s. A multivariate Cox proportional hazard model was constructed to evaluate the role of ERAT as a predictor of late recurrences (LR) for AF. RESULTS: In total, 127 patients (49.0%) experienced their last episodes of ERAT during the first (n = 65), second (n = 14), or third (n = 48) month of the 3-month blanking period (p < .001). One year freedom from ATAs was 97.8% in patients without ERAT compared with 95.4%, 64.3%, and 8.3% in patients with ERAT in the first, second, and third months after the index procedure, respectively (p < .001). Hazard ratios of LR according to the timing of the last episode of ERAT first, second, and third months after the procedure were 2.84, 16.70, and 119.75, respectively. CONCLUSIONS: The ERAT occurred in 49.0% of patients within the first 3 months after surgical ablation. The occurrence of ERAT within 3 months after surgical AF ablation was a significant independent predictor of LR. Hence, the currently accepted 3-month blanking period may be considered for redefining in patients with AF surgical ablation.
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Choi et al. (2020) conducted a cohort in Atrial fibrillation (n=259). Early recurrence of atrial tachyarrhythmia (ERAT) vs. No ERAT was evaluated on Late recurrences (LR) for AF (HR 2.84, 16.70, and 119.75, p=< .001). Early recurrence of atrial tachyarrhythmia within 3 months after surgical AF ablation strongly predicted late recurrence, with hazard ratios of 2.84, 16.70, and 119.75 for months 1, 2, and 3.
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