Key result
Genomic characterization of 12 EV-D68 strains from Beijing (2011-2015) revealed two circulating lineages with little association to the strains from the 2014 USA outbreak.
Observational (n=12)
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EV-D68 strains circulating in Beijing from 2011 to 2015 were phylogenetically distinct from those responsible for the 2014 USA outbreak.
A retrospective surveillance study on enterovirus D68 was performed in Beijing, China, following the largest and most widespread EV-D68 infection, which occurred in the USA. From January 2011 to July 2015, EV-D68 was identified in 12 individuals with respiratory infections in Beijing, China. The phylogenetic relationships based on the genomic sequence alignment showed that there were two lineages circulating in Beijing from 2011 to 2015. Eight EV-D68 strains belonged to group 1 and four belonged to group 3. All EV-D68 strains from Beijing in 2014 were separately clustered into subgroup II of group 1. Based on these results, we concluded that the Beijing EV-D68 strains had little association with the EV-D68 strains circulating in the 2014 USA outbreak.
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Zhang et al. (2016) conducted an observational in Enterovirus D68 respiratory infection (n=12). Enterovirus D68 infection was evaluated on Phylogenetic relationships based on genomic sequence alignment. Genomic characterization of 12 EV-D68 strains from Beijing (2011-2015) revealed two circulating lineages with little association to the strains from the 2014 USA outbreak.
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