Why the study?
Does moderate right coronary hypotension alter high-energy phosphates in the right ventricle of anesthetized dogs?
Population
Anesthetized dogs
Comparison
Right coronary perfusion pressure reduced to 60… vs RCPP kept constant at 100 mmHg
Design
Preclinical
Follow-up
20 min
Authors
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RV maintains energetic efficiency during moderate right coronary hypotension in dogs; leaves open translation to human RV ischemia.
Does moderate right coronary hypotension alter high-energy phosphates in the right ventricle of anesthetized dogs?
The right ventricle can increase its energetic efficiency to maintain high-energy phosphates during moderate right coronary hypotension, operating at a lower baseline energy level than the left ventricle.
Itoya et al. (1996) studied this question.
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