Why the study?
Does beta-adrenergic stimulation induce hypertrophy and maintain myofibrillar structure in isolated adult feline cardiomyocytes?
Population
Isolated adult feline cardiomyocytes maintained in culture for up to 30 days
Comparison
Beta-adrenergic stimulation (e.g., 1 x 10 M… vs Quiescent cultures
Design
Preclinical
Follow-up
up to 30 days
Authors
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Beta-adrenergic beating may drive hypertrophy in feline cardiomyocytes; leaves open in vivo relevance or therapeutic translation.
Does beta-adrenergic stimulation induce hypertrophy and maintain myofibrillar structure in isolated adult feline cardiomyocytes?
Beta-adrenergic activation of beating in cultured adult feline cardiomyocytes induces cellular hypertrophy and maintains organized myofibrillar structure.
Clark et al. (1991) studied this question.
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