Population
Isolated perfused rat heart
Design
Preclinical
Authors
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In an isolated perfused rat heart model, increasing heart rate via pacing does not significantly alter intracellular sodium concentration, despite a negative force-frequency relationship.
In an isolated perfused rat heart model, increasing heart rate via pacing does not significantly alter intracellular sodium concentration, despite a negative force-frequency relationship.
Butwell et al. (1991) studied this question.
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