Why the study?
Does treadmill training alter the contractile responsiveness of rat heart to extracellular Na+ and Ca2+?
Population
Perfused hearts isolated from adult female rats
Comparison
Treadmill training (endurance exercise) vs Sedentary lifestyle
Design
Preclinical
Authors
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No immediate clinical implications; leaves open whether exercise augments myocardial Ca2+ efflux in humans.
Does treadmill training alter the contractile responsiveness of rat heart to extracellular Na+ and Ca2+?
Endurance exercise training in rats alters myocardial contractile responsiveness to extracellular sodium and calcium, suggesting augmented myocardial calcium efflux.
Lankford et al. (1998) studied this question.
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