Population
Isolated single cells from the ventricles of ferret and rat hearts
Comparison
Manipulation of intracellular and extracellular… vs Baseline/control conditions
Design
Preclinical
Authors
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May modulate triggered activity in animal models; leaves open relevance to human Ca2+ handling.
In isolated rat and ferret ventricular myocytes, the fast calcium current is regulated by resting intracellular calcium and spontaneous calcium increases, but not by the size of the stimulated calcium transient.
Boyett et al. (1988) studied this question.
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