Population
Neurons dissociated from aortic-renal and celiac ganglia of C57BL/6J mice
Comparison
Angiotensin II at 200 nmol/L, with various… vs Baseline or blocker conditions
Design
Preclinical
Authors
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Suggests AT1-mediated sympathetic activation may influence renal function; leaves open clinical relevance pending in vivo studies.
Angiotensin II selectively activates a subpopulation of postganglionic sympathetic neurons via AT1 receptors, triggering calcium influx and potentially affecting kidney function in pathological states.
Ma et al. (2001) studied this question.
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